PHARMACOLOGICAL PROPERTIES

HGH 36IU contains somatropin synthesized using recombinant technology, identical to the human growth hormone. In children with endogenous growth hormone deficiency and Prader-Willi syndrome, somatropin enhances and accelerates the linear growth of the skeleton. In both adults and children, somatropin supports normal body structure by stimulating muscle growth and promoting fat mobilization. Visceral adipose tissue is particularly sensitive to somatropin. In addition to stimulating lipolysis, somatropin reduces the flow of triglycerides into fat depots.

Somatropin increases the concentration of insulin-like growth factor (IGF-I) and IGF-binding protein (IФFSB-3) in blood serum.

In addition to the above properties, the following effects of HGH 36IU were shown:

Lipid metabolism

Somatropin stimulates hepatic receptors of low-density lipoproteins (LDL) and affects the profile of lipids and lipoproteins in the blood serum. In general, the use of somatropin in patients with growth hormone deficiency leads to a decrease in serum levels of LDL and apolipoprotein B. There may also be a decrease in total cholesterol concentration.

Carbohydrate exchange

Somatropin increases the concentration of insulin, however, the concentration of fasting glucose does not usually change. Children with hypopituitarism may experience fasting hypoglycemia. Somatropin suppresses this condition.

Water-salt exchange

Lack of growth hormone is associated with a decrease in plasma and tissue fluid. Both of these indicators increase rapidly after treatment with somatropin. Somatropin contributes to the retention of sodium, potassium and phosphorus.

Bone metabolism

Somatropin stimulates bone metabolism. In patients with growth hormone deficiency and osteoporosis, prolonged treatment with somatropin leads to the restoration of the mineral composition and bone density.

Physical performance

Treatment with somatropin increases muscle strength and physical endurance. Somatropin also increases cardiac output, but the mechanism of this effect has not yet been elucidated. A reduction in peripheral vascular resistance may play a role in this.

Mental status

In patients with growth hormone deficiency, there may be a decrease in mental abilities and changes in mental status. Somatropin increases vitality, improves memory and affects the balance of neurotransmitters in the brain.