Lasix - diuretic.
Dosage forms and composition Dosage forms of Lasix: Tablets: round, almost white or white, on one side below and above the separation risks are engraved “DLI” (in strips of aluminum foil: 10 pcs., In a cardboard bundle 5 strips; on 15 pieces, in a cardboard pack 3 strips); Solution for intravenous (iv) and intramuscular (v / m) administration: a clear, colorless liquid (2 ml each in dark-colored glass ampoules with a break point, 10 pcs. In a blister plastic packaging, in a carton pack 1 package). The active ingredient of Lasix - furosemide: 1 tablet - 40 mg; 1 ml of solution - 10 mg. Auxiliary components: Tablets: starch, lactose, pregelatinized starch, magnesium stearate, colloidal silicon dioxide, talc; Solution: sodium hydroxide, sodium chloride, water for injection.
Lasix is a powerful, fast-acting diuretic related to sulfonamide derivatives. Furosemide is a blocker of the system of transport of ions of chlorine, sodium, potassium in the thick segment of the ascending knee of the loop of Henle, as a result of which its diuretic effect is determined by the drug entering the lumen of the renal tubules (implemented according to the principle of the mechanism of anion transport). The diuretic effect is due to the suppression of the reabsorption of sodium chloride in this section of the loop of Henle. In addition to enhancing the excretion of sodium, taking furosemide leads to secondary effects, which include increased potassium production in the distal part of the renal tubule and an increase in the amount of urine released by osmotically bound water. At the same time, excretion of magnesium and calcium ions is enhanced. When the canalicular secretion of furosemide decreases or when it is bound to albumin, which is localized in the lumen of the tubules (for example, in patients with nephrotic syndrome), the effect of Lasix is reduced.
|Package||40mg (15 pills)|